KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP9
All Species:
11.52
Human Site:
S175
Identified Species:
21.11
UniProt:
P55211
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55211
NP_001220.2
416
46281
S175
N
V
N
F
C
R
E
S
G
L
R
T
R
T
G
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
R64
K
S
T
G
M
T
S
R
S
G
T
D
V
D
A
Rhesus Macaque
Macaca mulatta
XP_001082859
416
46192
S175
N
V
N
F
C
R
E
S
G
L
S
T
R
T
G
Dog
Lupus familis
XP_865164
414
45235
S174
N
V
N
F
C
P
E
S
R
L
T
A
R
G
G
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
K214
N
V
H
F
T
G
E
K
D
L
E
F
R
S
G
Rat
Rattus norvegicus
P55215
452
50709
K214
N
V
H
F
T
G
E
K
D
L
E
F
R
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520982
366
40213
L147
M
K
R
R
F
R
L
L
H
F
E
V
A
V
E
Chicken
Gallus gallus
Q98943
424
47941
K185
N
I
H
F
S
S
E
K
D
L
E
Y
R
S
G
Frog
Xenopus laevis
P55866
282
32106
S69
N
N
K
N
F
H
S
S
N
M
A
V
R
N
G
Zebra Danio
Brachydanio rerio
NP_001007405
436
48445
S186
N
I
N
F
E
K
A
S
E
L
N
D
R
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
K108
N
V
D
A
Q
E
L
K
K
A
F
E
N
L
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
E254
I
I
N
N
E
H
F
E
Q
M
P
T
R
N
G
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
K176
I
I
N
N
K
N
F
K
T
M
P
P
R
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
93.9
76.9
N.A.
28.9
28.3
N.A.
52.8
31.1
22.6
47.2
N.A.
22.1
N.A.
21.6
32.2
Protein Similarity:
100
35.8
96.8
84.1
N.A.
46.9
46.2
N.A.
65.6
48.3
38.7
64.2
N.A.
35.8
N.A.
37.5
51
P-Site Identity:
100
0
93.3
66.6
N.A.
46.6
46.6
N.A.
6.6
40
26.6
46.6
N.A.
20
N.A.
26.6
20
P-Site Similarity:
100
0
93.3
66.6
N.A.
60
60
N.A.
6.6
60
33.3
60
N.A.
26.6
N.A.
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
0
8
8
8
8
0
8
% A
% Cys:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
24
0
0
16
0
8
0
% D
% Glu:
0
0
0
0
16
8
47
8
8
0
31
8
0
0
8
% E
% Phe:
0
0
0
54
16
0
16
0
0
8
8
16
0
0
0
% F
% Gly:
0
0
0
8
0
16
0
0
16
8
0
0
0
8
85
% G
% His:
0
0
24
0
0
16
0
0
8
0
0
0
0
0
0
% H
% Ile:
16
31
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
8
0
8
8
0
39
8
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
16
8
0
54
0
0
0
8
0
% L
% Met:
8
0
0
0
8
0
0
0
0
24
0
0
0
0
0
% M
% Asn:
70
8
47
24
0
8
0
0
8
0
8
0
8
16
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
16
8
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
8
8
0
24
0
8
8
0
8
0
77
8
0
% R
% Ser:
0
8
0
0
8
8
16
39
8
0
8
0
0
24
0
% S
% Thr:
0
0
8
0
16
8
0
0
8
0
16
24
0
16
0
% T
% Val:
0
47
0
0
0
0
0
0
0
0
0
16
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _